The Peter Attia Drive on Smash Notes

The Peter Attia Drive

Expert insight on health, performance, longevity, critical thinking, and pursuing excellence. Dr. Peter Attia (Stanford/Hopkins/NIH-trained MD) talks with leaders in their fields.

Episode notes last updated on June 17, 2019 21:19


Recently updated notes

#58 – AMA with sleep expert, Matthew Walker, Ph.D.: Strategies for sleeping more, sleeping better, and avoiding things that are disrupting sleep
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Qualy #73 - How can we change the food system when 10 companies control almost 90 percent of the calories we consume in the US?
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#83 - Bill Harris, Ph.D.: Omega-3 fatty acids
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Qualy #69 - Advice to parents and kids for creating a sustainable environment that’s going to prevent them from running into metabolic problems
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#82 - Mark Messier: Leadership, personal growth, and performing under pressure
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Qualy #65 - The three laws of medicine — Law #1: A strong intuition is much more powerful than a weak test
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#81 - Debra Kimless, M.D. & Steve Goldner, J.D.: Cannabis – the latest science on CBD & THC
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Qualy #61 - Rapamycin in cancer treatment
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#80 - Celebrity AMA #1: Fasting, rapamycin, performance vs. longevity, and more
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Qualy #57 - A primer on NAD+/NADH, its effect on lifespan/healthspan, and a review of the supplements
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#79 - Ric Elias: Earning the gift of life
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Qualy #53 - Screening for prostate cancer
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#78 - Sasha Cohen: The price of achievement, and redefining success
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Qualy #52 - Insights about berberine
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#77 – AMA #2 with sleep expert, Matthew Walker, Ph.D.: short sleep mutants, optimal sleep environment, sleep apnea, & rapid fire questions
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Qualy #46 - Rapamycin’s effects on cancer, cardiovascular disease, and neurodegeneration
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#76 - Kyle Kingsbury: Finding meaning, depression, and psychedelics
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Qualy #43 - What are Peter’s thoughts on fasting and ketosis for females?
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#75 - David Light: Zantac recall due to cancer concerns – what you need to know
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Qualy #38 - Finding meaning in struggle and why we are less happy than ever (David Foster Wallace)
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#74 – Jason Fried: Optimizing efficiency and work-life balance
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Qualy #33 - How silent bravado and incessant striving can lead to a functional (and actual) death, and why Paul is critical of the current state of psychiatry
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#73 - AMA #9: NAD & metformin, fat-burning zone, creatine, estrogenization of men, emergency kit for cold & flu, and more
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Qualy #29 - Fasting as a powerful drug in the toolbox of medicine (sneak peek of Paul Grewal's upcoming episode)
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#72 - Dan Harris: 10% happier – meditation, kindness, and compassion
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Qualy #26 - What is Peter looking to achieve and monitor with his blood glucose monitor?
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#71 - Katherine Eban: Widespread fraud in the generic drug industry
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Qualy #24 - What are the “ABCs” of Alzheimer’s prevention?
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#70 - David Sinclair, Ph.D.: How cellular reprogramming could slow our aging clock (and the latest research on NAD)
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Qualy # 19 - A unifying theory of aging
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#69 - Ronesh Sinha, M.D.: Insights into the manifestation of metabolic disease in a patient population predisposed to metabolic syndrome, and what it teaches us more broadly
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Qualy #16 - How much does cognitive activity ward off cognitive decline?
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#68 - Marty Makary, M.D.: The US healthcare system—why it’s broken, steps to fix it, and how to protect yourself
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Qualy #9 - The importance of exercise for brain health
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#67 - AMA #8: DNA tests, longevity genes, metformin, fasting markers, salt, inflammation, and more
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Qualy #6 - What are the best lab tests to request specifically for longevity
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#66 - Vamsi Mootha, M.D.: Aging, type 2 diabetes, cancer, Alzheimer’s disease, and Parkinson’s disease – do all roads lead to mitochondria?
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Qualy #1 - What are Peter's thoughts on alcohol consumption and health?
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#65 - Rick Doblin, Ph.D.: MDMA— the creation, scheduling, toxicity, therapeutic use, and changing public opinion of what is possibly the single most important synthetic molecule ever created by our species
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#64 - Zol Kryger, M.D.: Navigating the sometimes shady world of plastic surgery—understanding potential complications of common procedures and how to reduce your risk by choosing the right doctor and asking the right questions
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#63 - AMA #7: Exercise framework, deadlifting, lower back pain, blood pressure, nootropics, CGM, and more
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#62 - Keith Flaherty, M.D.: Deep dive into cancer—History of oncology, novel approaches to treatment, and the exciting and hopeful future
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#61 - Rajpaul Attariwala, M.D., Ph.D.: Cancer screening with full-body MRI scans and a seminar on the field of radiology
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The one-year anniversary episode with Olivia Attia: Reflecting on the past year and looking forward to exciting times ahead
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#60 - Annie Duke, decision strategist: Poker as a model system for life—how to improve decision making, use frameworks for learning, and apply ‘backcasting’ to boost your odds for future success
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#59 - Jason Fung, M.D.: Fasting as a potent antidote to obesity, insulin resistance, type 2 diabetes, and the many symptoms of metabolic illness
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#57 – Rick Rubin, legendary music producer: collaborating with sensitive psyche of greatest living musicians, and his personal story of weight loss and spiritual quest
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#56 - Jocko Willink, retired Navy SEAL, Part II of II: Sleep, fasting, raising kids, discipline, taking ownership, and the impact of war
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#55 - Jocko Willink, retired Navy SEAL, Part I of II: objective, strategy & tactics, leadership, protocols, dealing with death, and applying the many lessons learned from war
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#54 – Kevin Sayer, CEO of Dexcom: Continuous glucose monitors – impact of food, sleep, and stress on glucose, the unmatched power of CGM to drive behavioral change, and the exciting future of CGM
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#53 - AMA #6: Fasting framework, vitamin supplementation, antioxidants, time management, problem-solving, and more
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#52 - Ethan Weiss, M.D.: A masterclass in cardiovascular disease and growth hormone - two topics that are surprising interrelated
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The Ayrton Senna Episode (re-release): Celebrating the greatest driver in Formula 1 history and the cautionary tales of driven individuals
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#51 - Robert Sapolsky, Ph.D.: The pervasive effect of stress - is it killing you?
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#50 - AMA #5: calcium scores, centenarian olympics, exercise, muscle glycogen, keto, and more
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#49 – Matthew Walker, Ph.D., on sleep – Part III of III: The penetrating effects of poor sleep from metabolism to performance to genetics, and the impact of caffeine, alcohol, THC, and CBD on sleep
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#48 – Matthew Walker, Ph.D., on sleep – Part II of III: Heart disease, cancer, sexual function, and the causes of sleep disruption (and tips to correct it)
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#47 – Matthew Walker, Ph.D., on sleep – Part I of III: Dangers of poor sleep, Alzheimer's risk, mental health, memory consolidation, and more.
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#46 - Chris Masterjohn, Ph.D.: Navigating the many pathways to health and disease - NAD and sirtuins, methylation, MTHFR and COMT, choline deficiency and NAFLD, TMAO, creatine, and more
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#45 - AMA #4: sleep, jet lag protocol, autophagy, metformin, and more
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#44 - Jeremy Schaap, ESPN journalist: upsets, doping, triumphs, and the importance of sports
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#43 - Alan Bauman, M.D.: The science of male and female hair restoration - how to protect, enhance, and restore the appearance and health of the hair and scalp
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#42 - Avrum Bluming, M.D., and Carol Tavris, Ph.D.: Controversial topic affecting all women—the role of hormone replacement therapy through menopause and beyond—the compelling case for long-term HRT and dispelling the myth that it causes breast cancer
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#41 - Jake Kushner, M.D.: How to thrive with type 1 diabetes and how everyone can benefit from the valuable insights
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#40 - Tom Catena, M.D.: The world’s most important doctor – to nearly a million patients – saving countless lives in the war-torn and remote villages of Sudan
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#39 - Ted Schaeffer, M.D., Ph.D.: How to catch, treat, and survive prostate cancer
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#38 - Francisco Gonzalez-Lima, Ph.D.: Advancing Alzheimer’s disease treatment and prevention – is AD actually a vascular and metabolic disease?
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#37 - Zubin Damania, M.D.: Revolutionizing healthcare one hilariously inspiring video at a time
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#36 - Eric Chehab, M.D.: Extending healthspan and preserving quality of life
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#35 - Nir Barzilai, M.D.: How to tame aging
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#34 - Sam Harris, Ph.D.: The transformative power of mindfulness
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#33 - Rudy Leibel, M.D.: Finding the obesity gene and discovering leptin
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#32 - Siddhartha Mukherjee, M.D., Ph.D.: new frontiers in cancer therapy, medicine, and the writing process
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#31 - Navdeep Chandel, Ph.D.: metabolism, mitochondria, and metformin in health and disease
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#30 - Thomas Seyfried, Ph.D.: Controversial discussion—cancer as a mitochondrial metabolic disease?
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#29 - Apolo Anton Ohno: 8-time Olympic medalist – extreme training, discipline, pursuing perfection, and responding to adversity
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#28 - Mark and Chris Bell: steroids, powerlifting, addiction, diet, training, helping others, documentaries, and living your best life
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#27 - David Sinclair, Ph.D.: Slowing aging – sirtuins, NAD, and the epigenetics of aging
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#26 - AMA #3: supplements, women’s health, patient care, and more
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#25 - Scott Harrison: transformation, finding meaning, and taking on the global water crisis
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#24 - Tom Dayspring, M.D., FACP, FNLA – Part V of V: Lp(a), inflammation, oxLDL, remnants, and more
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#23 - Tom Dayspring, M.D., FACP, FNLA – Part IV of V: Statins, ezetimibe, PCSK9 inhibitors, niacin, cholesterol and the brain
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#22 - Tom Dayspring, M.D., FACP, FNLA – Part III of V: HDL, reverse cholesterol transport, CETP inhibitors, and apolipoproteins
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#21 - Tom Dayspring, M.D., FACP, FNLA – Part II of V: Lipid metrics, lipid measurements, and cholesterol regulation
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#20 - Thomas Dayspring, M.D., FACP, FNLA – Part I of V: an introduction to lipidology
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#19 - Dave Feldman: stress testing the lipid energy model
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#18 - Richard Isaacson, M.D.: Alzheimer’s prevention
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#17 - Mike Trevino: life-lessons from ultra-endurance, mindset, hard work, and removing limitations
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#16 - Formula 1 (with Paul Conti): the best drivers, Ayrton Senna, and the cautionary tales of driven individuals
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#15 - Paul Conti, M.D.: trauma, suicide, community, and self-compassion
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#14 - Robert Lustig, M.D., M.S.L.: fructose, processed food, NAFLD, and changing the food system
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#13 - Brett Kotlus, M.D.: How to look younger while you live longer
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#12 - Corey McCarthy: Overcoming trauma, dealing with shame, finding meaning, changing the self-narrative, redemption, and the importance of gratitude
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#11 - AMA #2: the Nothingburger — results from Peter’s week-long fast between two weeks of nutritional ketosis — and answering questions on all things fasting
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#10 - Matt Kaeberlein, Ph.D.: rapamycin and dogs — man’s best friends? — living longer, healthier lives and turning back the clock on aging, and age-related diseases
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#09 - David Sabatini, M.D., Ph.D.: rapamycin and the discovery of mTOR — the nexus of aging and longevity?
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#08 - Tom Bilyeu: nutrition, fasting, meditation, mindset, immortality, and the secret formula of fulfillment
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#07 - Deep Dive: Lp(a) — what every doctor, and the 10-20% of the population at risk, needs to know
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#06 - D.A. Wallach: music, medicine, cancer screening, and disruptive technologies
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#05 - Dom D’Agostino, Ph.D.: ketosis, n=1, exogenous ketones, HBOT, seizures, and cancer
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#04 - AMA #1: alcohol, best lab tests, wearables, finding the right doc, racing, and more
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#03 - Ron Krauss, M.D.: a deep dive into heart disease
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#02 - Rhonda Patrick, Ph.D.: the performance and longevity paradox of IGF-1, ketogenic diets and genetics, the health benefits of sauna, NAD+, and more
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#01 - Tim Ferriss: depression, psychedelics, and emotional resilience
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#00 - Sneak Peek: The Peter Attia Drive
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