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It is pretty safe but there have been reports of bad things happening, usually while someone did something sketchy. One doctor with a suspended medical license, for example, ordered some botulism toxin which was meant for lab purposes, he improperly diluted it, and injected too much. No one died, but a few people got sick and went to a hospital.

When you are a young founder, fresh out of college, chances are you don't know a lot and you are not actually very good at many things. At his point, it makes a lot of sense to pick a consumer startup that has a lot of market risk, but low execution risk.

Market risk is the risk that nobody wants your product. However, if you can find something that users love, you just keep making more of it, and your chances of winning big are quite high. Thinks companies like Facebook or Snapchat.

Once you mature and gain skills, it makes sense to work on a startups with less market risk and more execution risk, a startup that you know people already want, but it is very hard to deliver correctly. With Atrium, for example, Justin knew that legal market was already huge, and it was also ripe for innovation.

When he was considering the topic of heredity, he thought about what’s normally talked about with heredity. We talk about it all the time as we make connections when different generations having similar traits.

Jamie Morton states that we have not heard everything that's in the book because when we think we have, each chapter is dredged out of nowhere. This includes eye watering imagery that is unbelievable, which is why they must continue reading.

At first, it was to seduce her, but now, something is different. He speculates if he has met his equal in his sexual symbolic world. He wants to show dominance over Belinda, but then realizes he doesn’t want to do that while they are in the hotel lobby.

It all depends on your aspirations. If you desire to start a billion-dollar venture backed high-growth company, you are going to have to work harder. If you are satisfied with a small business that just makes money to live off, chance are you won't work as hard.

Men who sleep 5 to 6 hours a night we'll have a level of testosterone,which is that of someone 10 years their senior. So elective sleep will age you by a decade, in terms of wellness, muscle strength and sexual performance.

Flexport goes after their competitor's clients and shows their value proposition - they can deliver visibility and control over their freight, at the same price point as their legacy providers.

At some point, it makes no sense for those clients not to convert over to Flexport.

You can join a local chapter of the National Speleological Society at caves.org.

Cindy also wrote a guide here at https://cindywu.org/@cindy/so-you-want-to-cave-DF3MNY

Bryan Helmig and Wade Foster were living in Columbia, Missouri, a college town of 100k people, where they were known as "The people who could do internet stuff."

Every now and then they would get asked to do one-off API integrations, and eventually, they realized it could be a business all on its own.

Brandon asks Pat about the science behind going viral in Reddit and Hacker News with what he publishes on his site. Is there any way to replicate virality or is more of getting lucky?