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Back to #887: Q&A with Tim — The 4-Hour Workweek in a World of AI, Rebuilding Personal Agency, The 4-Hour Body After 40, and More.

What One-day Depression Treatment Did Tim Ferriss Describe?

Tim Ferriss described a depression protocol, used at Stanford and elsewhere, that clinics compressed from about three or four months to one week, and then to a single day by adding D-cycloserine. He called that drug a neuroplasticity agent that makes a person more malleable before the stimulation. Nolan Williams and others did the one-week version at Stanford. Jonathan Downer at Ampa Health was, in his account, one of the pioneers of the one-day version. He called D-cycloserine, sometimes abbreviated DCS, the most established drug for treating depression.

The stimulation he named is intermittent theta burst. He said the hardware does not have to be an Ampa Health device. Brainsway is the hardware market leader in his telling, and MagVenture is another maker. He also said the approach has been applied to generalized anxiety disorder, and that he sees possible uses for OCD, which he called a close cousin of that anxiety in his own case, and for sleep. From his personal experience, he looks for a clinician familiar with accelerated TMS and with the one-day protocol plus D-cycloserine. Most people, he said, cannot spare five days away from work, and more days in the clinic mean more clinician time and a higher cost.

Grokipedia·Tim Ferriss

Transcript

#887: Q&A with Tim — The 4-Hour Workweek in a World of AI, Rebuilding Personal Agency, The 4-Hour Body After 40, and More ·

The Tim Ferriss Show

More from this episode

  1. What Does the Four-hour Workweek Look Like With AI?Tim Ferriss says the four-hour workweek in a world of AI agents still follows the book's four-step process: definition, elimination, automation, and liberation.
  2. Why Does Life Stage Matter for the 4-hour Workweek?Tim Ferriss wrote The 4-Hour Workweek when he was 29, and he is now 49.
  3. How Do You Stop Overthinking and Start Acting?Tim Ferriss says a bias toward immediate small actions is what he has seen break a cycle of overthinking, avoidance, and inaction.
  4. What Does Tim Ferriss Ask Podcast Guests?Tim Ferriss would ask a guest what they are most excited about and what they are doing about it, or what keeps them up at night and what they are doing about…
  5. What Did Tim Ferriss Notice After 30 Days of Oryx?Tim Ferriss says he used Oryx, vision software he spells O-R-Y-X, for 30 days at eight minutes a day.
  6. What Does Investing 10 Times More in Health and Relationships Look Like?Tim Ferriss borrows a heuristic from Ramit Sethi and is trying to invest 10 times more in health and 10 times more in relationships.
  7. What Happens If You Over-engineer Your Life?Tim Ferriss agrees 100% that if you over-engineer your life, you are almost definitionally less receptive to life that emerges.
  8. What Does John Sarno Say Causes Back Pain?Tim Ferriss says Healing Back Pain by John Sarno argues that almost all back pain is psychosomatic.
  9. Does the 4-hour Body Still Apply After 40?Tim Ferriss says the basic principles in The 4-Hour Body still apply after 40 and after 50.
  10. What Is on Grief and Grieving?Tim Ferriss names On Grief and Grieving as the book people he knows, loves, and trusts have recommended most for grieving.

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