Smash Notes
Why Does Peter Attia Swap Progesterone Pills for an IUD? · Huberman Lab

Huberman Lab

Exercise, Nutrition, Hormones for Vitality & Longevity | Dr. Peter Attia

My guest this episode is Dr. Peter Attia, M.D., who trained at Stanford University School of Medicine, Johns Hopkins Hospital and the National Institutes of Health (NIH). Dr. Attia is host of The Drive podcast and is a world expert on behavioral approaches, nutritional interventions, supplementation and pharmacological techniques to improve lifespan…

Notes

  1. Peter Attia calls lipoprotein little a the single most prevalent genetic driver of atherosclerosis. Full answer

  2. On Huberman Lab, body fat is the least interesting of the four results a DEXA scan produces and ranks fourth for health. Full answer

  3. On Huberman Lab, a study done in Australia took older women who looked to be in their sixties or seventies and who had never lifted weights, and put them on a… Full answer

  4. Peter Attia defines the marginal decade as the last decade of life and says everyone will have one. Full answer

  5. On Huberman Lab, cardiorespiratory fitness shows a profound link to all-cause mortality. Full answer

  6. Going from completely sedentary to 15 metabolic equivalent hours a week produces probably a 50 percent reduction in risk, equal to half the benefit of going… Full answer

  7. Peter Attia has cycled nicotine on and off for the last 10 years and calls it a concentration enhancing substance. Full answer

  8. On Huberman Lab, half a recommended dose of armodafinil, prescribed by a doctor, was a powerful stimulant. Full answer

  9. On Huberman Lab, a low dose of progesterone through the last half of the luteal phase, and sometimes through the entire luteal phase, makes all premenstrual… Full answer

  10. On the show, the relative risk increase of breast cancer in the estrogen plus synthetic progesterone group versus placebo was 25 to 27 percent. Full answer

  11. On Huberman Lab, estrogen plus synthetic progesterone reached one breast cancer case in a thousand and just hit statistical significance at a p-value of 0.05. Full answer

  12. On the show, hormone replacement therapy for a woman is preferred from her gynecologist, with an endometrial ultrasound every year and a pap smear every year… Full answer

  13. On Huberman Lab, insulin suppresses sex hormone binding globulin. Full answer

  14. On Huberman Lab, a clinician stopped using Anavar to lower SHBG. The question was whether Anavar was still used because Anavar is too potent. Full answer

  15. Peter Attia gives patients who arrive on a long supplement list a homework exercise: answer seven questions for every supplement. Full answer

  16. Peter Attia says the only purpose of fixing testosterone is to give someone the capacity to work harder, recover more from workouts, and experience more… Full answer

  17. On Huberman Lab, dietary cholesterol plays no role in serum cholesterol and has no bearing on it. Full answer

  18. On Huberman Lab, semaglutide is catabolic across the board, so patients lose fat and also lose muscle. Full answer

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