Why Can Weight Loss Drugs Leave You Frail?

Will Ahmed says a GLP-1 is a meaningful shift for the body, and typically about 50% of the weight someone loses is fat and 50% is muscle. The muscle share is how people can sometimes end up quite frail even after losing a considerable amount of weight.

Knowing someone is on a GLP-1 lets Whoop push activity and a little strength training, even if it is only body weight, so the person does not end up losing weight. The right diet includes protein, and anecdotal success around creatine while on a GLP-1 is treated as super important.

Jason Calacanis added a GLP on a mirrored phone. The plan called for 9,800 steps, two strength activities a week, hydration, protein seven days a week, and a check-off after each dose, following a short script about how often the dose is taken.