David Rosenthal says that in February 1993, Seinfeld moved from Wednesday to Thursday and the ratings rose 57%. In one week it went from the 45th most popular show on television to the 5th.

David Rosenthal says a huge part of the jump was the time slot. Ben Gilbert says everyone at the network expected that a show after Cheers would get good ratings and still lose viewers on the way from Cheers to the next show. The only question was how large the drop-off would be. Ben Gilbert says Seinfeld gained audience over Cheers. It retained the Cheers audience, and new people tuned in just to see the next episode. David Rosenthal says on a first-run Thursday night it held the full lead-in. By the en

Dave Morin told Jason Calacanis on Angel that a startup eats every free hour, so you schedule life first. Struggling founders should book yoga or meditation for an hour or ninety minutes, cut sugar and alcohol, and eat more plants. A date night is not optional. At Sunrise, which he started with Columbia neuroscientist Rebecca Brachman, they funded phase 2 trials. Ketamine, including IV trials at Stanford for people who cannot get out of bed, can ease a crisis for weeks, he said, but only with a psychiatrist. Not at a rave, and not in a clinic run like dialysis. He pointed listeners to Michael Pollan's How to Change Your Mind.

Selling "early" can enable the founding team to take some future risk off the table, as well as give some money back to the entire team, propelling each individual employee forward.

In the best acquisition, 1+1=3, meaning that both the acquirer and the company being acquired benefit from being with each other.

For example, a startup might gain immediate access to global scale, while an incumbent gains a leg up in technology.

Ed Elson says a Tesla and SpaceX merger would probably mean SpaceX buys Tesla and pays Tesla investors in SpaceX stock. Shareholders would convert Tesla shares into SpaceX shares at a price the boards set. RBC predicts a 20 to 30 percent premium.

He says that premium can disappear. The payment is SpaceX stock, so a holder can look 20 percent richer and then lose the premium if SpaceX falls 20 percent the next day. Ed Elson says that could easily happen because the float is still about 15 to 20 percent, while NVIDIA and Microsoft, which he calls actual multi-trillion-dollar companies, have floats near 100 percent. A smaller float, he says, is easier for very large shareholders to move. He ca

Today it powers 30% of all websites in the world, and it is easy to think think that Matt, the founder, had it all figured out in the early day. In reality, WordPress was just a part time project, while he was going to school. Unbelievable, but true!

Jim realized that while he has an appetite for risk, that won't be true for many of his clients, and everyone should have a portfolio that optimized for their comfort level. Some people would prefer to make less money with less risk, and that is totally okay. What's most important is that your start investing as early as you can, making the most gain from the compounding interest.

A startup is a multi-year adventure and you really want to ask yourself - Why are you doing this? Choose carefully.

Also, demand is the most important thing when you are starting out. Validate fast. Don't even worry about building anything. Pick up the phone and call people.

When it comes time to find investors, prioritize those that have founder empathy.

Most important companies that are going to exist, have not existed before, so to fund them one has to take risk ,and yet while technology changes, but human nature is a constant, and there's always going to be fraud. By funding scientists, which already go through publications and peer reviews, Lux gets to fund people who know how to backup findings with evidence.

Yes. Living in Palo Alto ten years ago, Sahil felt like he had missed the boat. But, fast-forward to now, having worked his way up, he was able to meet some of the known people in Silicon Valley, and new entrepreneurs have come up, forming new social circles. It's possible to do this anywhere, so long as there's a community willing to work hard.

Henry Shukman says the great way is the great reality, one single whole that excludes nothing. It has no size. It is free of time, yet it allows time to happen and lets everything unfold. The poem opens with the line that the great way is not difficult and just dislikes choosing, the same ground as preferences and reactivity.

The line comes from the third ancestor in Chinese Chan, or Zen Buddhism, in a poem called the Shin Shin Ming, or the Shin Jin Mei in Japanese, about three pages long. People have pored over it for millennia. The great way is not something a person sees out there. It is what a person actually is, and what all of us are. It goes beyond self and other and beyond self and

Twilio separated their sales teams into Hunters and Farmers. One group of sales people were tasked to find new leads, while the other were solely focused to upsell their existing base. That strategy, combined with marketing focused around specific enterprise pain points, was what enabled Twilio to transition from individual developers and move into enterprise.